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Avana

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  • Detail
    Product NameAvana
    componentAvanafil
    InfluenceED Treatment
    side effectDrop in blood pressure, bloodshot eyes, headache, facial flushing, heart palpitations, etc.
    How to takeTake one tablet 30 minutes to 1 hour before sexual activity
    ManufacturerSunrise Remedies

    Product Details

    ※Packaging may vary depending on the shipping period

    Features of Avana

    Avana is a generic version of Stendra manufactured by Sunrise Remedies.
    It is classified as a fourth-generation ED (Erectile Dysfunction) treatment, offering advantages such as rapid onset and minimal dietary influence, making it a highly user-friendly ED medication.
    Additionally, Avana provides the same efficacy as the original drug at a lower price, offering excellent cost performance.

    Differences from Other ED Treatments

    ItemAvanafilSildenafilVardenafilTadalafilUdenafil
    Original DrugStendraViagraLevitraCialisZydena
    DurationApprox. 3–6 hoursApprox. 4–5 hoursApprox. 5–8 hoursApprox. 24–36 hoursApprox. 8–13 hours
    Onset Time15–30 minutes30–60 minutes15–30 minutes1–4 hours40–60 minutes
    Side EffectsLess likelyMore likelyRelatively fewerLess likelyRelatively fewer
    Dietary InfluenceMinimal impactMore likely impactedMinimal impactLess impactedMinimal impact

    Avanafil, the active ingredient in Avana, is characterized by its rapid onset and fewer side effects compared to other ED medications.
    Like Levitra, which is known for its quick action, Avana typically takes effect within 15–30 minutes after ingestion.
    Even if taken after intimate moments with a partner, it can still work effectively, offering greater flexibility in usage timing.
    In terms of efficacy, Avana is comparable to Viagra and Levitra, while being less affected by diet and having fewer side effects.
    Therefore, it is recommended for those who experienced strong side effects with other ED medications or for first-time users.

    Effects of Avana

    The main ingredient in Avana, avanafil, inhibits the erection-blocking enzyme PDE-5 (phosphodiesterase type 5).
    PDE-5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), which promotes erections.
    When cGMP is broken down, achieving an erection becomes difficult, a condition known as ED (Erectile Dysfunction).
    Avanafil works by inhibiting the PDE-5 enzyme, dilating blood vessels around the penis and relaxing smooth muscle tissue in the corpus cavernosum.
    Through this mechanism, blood vessels dilate and muscles relax, allowing more blood to flow easily into the penile corpus cavernosum, thereby facilitating an erection.

    Duration of Avana

    The effects of Avana typically last approximately 3–6 hours.
    However, erections occur only with sexual stimulation or arousal, so it does not affect daily life.
    Avana is one of the fastest-acting ED medications, with effects starting as early as 15 minutes after ingestion.
    Peak blood concentration is reached in about 30 minutes, so it is recommended to take it 15–30 minutes before sexual activity for optimal results.

    Clinical Trial Results

    Avanafil (50mg, 100mg, 200mg)
    Participants646 men with mild to severe ED
    Trial Duration12 weeks
    Sexual Intercourse Success Rate
    (Avanafil)
    64–71%
    Sexual Intercourse Success Rate
    (Placebo)
    27%
    Trial results showed that some participants experienced effects within 15 minutes of ingestion, with successful intercourse still possible even 6 hours later. All three doses demonstrated significant improvement.

    Comparison of Avana Effects by Dosage

    ●Test Results for Different Avanafil Doses
    DosageIIEF Score ImprovementInsertion Success Rate (SEP2)Intercourse Success Rate (SEP3)
    50mg5.418.2%27.8%
    100mg8.327.2%43.4%
    200mg9.529.8%44.2%
    ※This table can be scrolled.

    Avanafil is an ED medication where higher doses yield more pronounced effects.
    Clinical trials showed that the 50mg dose improved the IIEF (International Index of Erectile Function) score by 5.4 points, with an intercourse success rate of 27.8%, indicating moderate improvement.
    The 100mg dose improved the score by 8.3 points, and the 200mg dose by 9.5 points, with intercourse success rates of 43.4% and 44.2%, respectively, showing significant improvement.
    However, the difference between 100mg and 200mg is minimal, so most users may find 100mg sufficient for desired effects.

    User Reviews of Avana

    Avana has received many positive reviews, with its rapid onset being praised as its greatest appeal.
    Many users report "noticeable effects within about 10–20 minutes after ingestion," and its speed is favorably compared to Levitra.
    Additionally, reviews such as "almost no side effects" or "only mild headaches" are common, making it a preferable option for those who experienced stronger side effects with Viagra or Levitra.
    Regarding erection strength and duration, there are positive comments like "comparable to or even stronger than Viagra."
    Since the price is less than half that of Stendra, it is also praised for its cost-effectiveness.
    While there are negative reviews such as "no noticeable effects" or "not suitable for a second round," overall, it is regarded as "an ED medication worth trying."

    Checking Avana's Expiration Date

    The expiration date of Avana is clearly printed on the back of the packaging.
    In the box at the top right of the packaging, you will find information marked as "B.NO," "M.D," and "E.D," which stand for the following:

    Avana expiration date sample image
    ・B.NO (Batch Number): SE-1113
    ・M.D (Manufacturing Date): 04/24 (April 2024)
    ・E.D (Expiry Date): 03/26 (March 2026)

    As shown above, the packaging includes the product's batch number, manufacturing date, and expiration date. Please confirm these before use.
    To ensure efficacy, use the product within the expiration date, whether opened or unopened.

    Frequently Asked Questions About Avana

    FAQs


    Q1:What is Avana's most notable feature?
    A1:Avana's most notable feature is its rapid onset, with effects starting as quickly as 15 minutes after ingestion. It is also minimally affected by food and has fewer side effects compared to other ED medications. These characteristics make Avana a balanced ED treatment offering speed, food tolerance, and low side effects.


    Q2:Can Avana be taken with other ED medications?
    A2:Concurrent use with other ED medications is not recommended, as it may increase side effects. ED medications work by dilating blood vessels and improving blood flow. Combining multiple medications could lead to a sharp drop in blood pressure, causing headaches, dizziness, palpitations, or even fainting. Therefore, avoid taking multiple ED medications simultaneously.

    Related Pages for Avana


    Avanaite
    Avanafil Product List
    Stendra Generic Products

    Administration Method & Usage Instructions

    Timing of Administration

    Take one tablet with warm or cool water approximately 30 minutes to 1 hour before sexual activity.
    The maximum single dose is 200mg, but first-time users of avanafil are recommended to start with 50mg.
    It is advisable to try a lower dose initially, observe the effects, and gradually increase to find the optimal dosage for your needs.
    Taking the medication on an empty stomach enhances absorption and maximizes efficacy.
    Please ensure at least 24 hours between doses.
    This prevents excessive intake, reduces physical burden, and maintains stable effectiveness while ensuring safety.

    Food Interaction

    Although avanafil is less affected by food, it is not entirely immune to interference. Consuming it with fatty drinks like whole milk may create a film in the stomach lining, hindering absorption.
    Therefore, it is recommended to take it 30 minutes before meals to ensure effective absorption and minimize food interference.
    If taken after meals, allow approximately 2 hours.
    Insufficiently digested food may affect drug absorption.
    High-fat meals such as grilled or fried foods may require more than 2 hours for digestion, so taking it on an empty stomach is preferable.
    You may eat normally after the drug has been absorbed (about 1 hour later).

    Alcohol Interaction

    Although concurrent alcohol consumption is possible, the vasodilatory effect may accelerate intoxication, so excessive drinking should be avoided.

    Contraindications

    ・Individuals with cardiovascular diseases (heart/vascular disorders) for whom sexual activity is not recommended

    ・Patients with severe liver dysfunction

    ・Patients with severe kidney dysfunction or undergoing dialysis

    ・Individuals with hypotension or uncontrolled hypertension

    ・Those who have undergone heart surgery within the last 6 months or have a history of stroke/cerebral hemorrhage/myocardial infarction

    ・Patients with blood disorders such as multiple myeloma, leukemia, or sickle cell anemia

    ※Please strictly follow medical advice when taking this medication.

    Side Effects

    Primary Side Effects

    The main side effects of Avanafil include:
    ・Headache
    ・Dizziness
    ・Facial/neck/chest flushing or warmth
    ・Cold symptoms (nasal congestion, runny nose, sinus pain, sore throat, etc.)
    ・Diarrhea
    ・Constipation
    ・Stomach discomfort
    ・Back pain
    ・Upper respiratory infection
    ・Influenza
    ・Bronchitis
    ・Joint pain
    ・High blood pressure

    These side effects are typically caused by vasodilation effects, and impacts on the digestive and immune systems may also lead to cold-like symptoms.
    Most cases involve mild and temporary symptoms, but if symptoms become severe or persistent, medical consultation should be sought promptly.

    Severe Symptoms

    The following serious side effects may occur:
    ・Hives
    ・Difficulty breathing
    ・Swelling of the face/lips/tongue/throat
    ・Vision loss
    ・Dizziness
    ・Nausea
    ・Painful erection
    ・Numbness or tingling in the chest/arms/neck/jaw
    ・Vision changes
    ・Tinnitus
    ・Sudden hearing loss
    ・Pain/swelling/warmth/redness in hands or feet
    ・Shortness of breath
    ・Painful erections
    ・Erections lasting more than 4 hours

    If any of these symptoms appear, they may indicate serious health risks, and immediate medical attention should be sought.

    Rare Symptoms

    Avanafil may cause the following uncommon side effects:
    ・Priapism (persistent erection)
    ・Sudden vision loss in one or both eyes
    ・Sudden hearing impairment or deafness

    These symptoms may lead to serious health damage if left untreated, and immediate medical consultation is necessary.

    Managing Side Effects

    Management Options
    • Headache: Over-the-counter pain relievers like acetaminophen or ibuprofen may alleviate symptoms
    • Diarrhea/abdominal pain: Stomach medicine or intestinal regulators can improve symptoms
    • Facial flushing: Dimming lights can reduce noticeable flushing to others
    If side effects are pronounced at a 200mg dose, reducing the dosage using a pill cutter may help.
    However, if severe side effects occur, discontinue use immediately and seek medical attention.

    Drug Contraindications

    Prohibited Combinations

    Prohibited combination drugs refer to medications that are contraindicated with Avanafil (Avana) and must not be taken simultaneously.
    ・Nitrates and nitric oxide donors
    (Nitroglycerin, Amyl nitrite, Isosorbide dinitrate)
    Concurrent use may enhance blood pressure-lowering effects.

    ・Amiodarone hydrochloride
    (Ancarone tablets)
    Combination may intensify the QT interval prolongation caused by amiodarone.

    ・CYP3A4 inhibitors
    (Antifungals, antibiotics, HIV medications, Telithromycin, Nefazodone, Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Nelfinavir, Atazanavir, Clarithromycin, Telithromycin, etc.)
    May increase blood concentration and prolong half-life of this medication.

    Precautions for Drug Combinations

    Drugs requiring cautious use with Avanafil refer to medications that require special attention when combined.
    ・Grapefruit (including juice)
    Contains furanocoumarins that inhibit metabolic enzymes, delaying drug breakdown.
    May lead to excessive absorption of drug components, increasing efficacy and side effect risks.

    ・CYP3A4 inhibitors/inducers
    Ritonavir, Saquinavir, Darunavir

    ・Antihypertensive drugs
    As Avanafil has blood pressure-lowering effects, concurrent use with antihypertensives may cause orthostatic hypotension symptoms such as dizziness or lightheadedness.

    Storage Method

    ・Store in a cool, dry place away from direct sunlight.

    ・Keep out of reach of children.

    ・Do not transfer to other containers to prevent accidental ingestion or quality deterioration.

    ・When dividing single-dose packaged medicine, reseal remaining portions and consume within 2 days.

    ・Discontinue use after the expiration date printed on the package.

    Manufacturer

    Sunrise Pharmaceuticals
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